Systematic Errors in Computed Alkane Energies Using …
2019-1-3 · Energies computed by B3LYP and other popular DFT functionals are flawed by systematic errors, which can become considerable for larger molecules. These errors, predominately due to inadequacies in assessing longer-range nonbonded attractive effects (dispersion), are illustrated by the isodesmic stabilization energies of n-alkanes (based on methane and ethane, which have no …Plus de détails
Metabolic hypothesis for human altriciality | PNAS
2012-9-18 · The classic anthropological hypothesis known as the "obstetrical dilemma" is a well-known explanation for human altriciality, a condition that has significant implications for human social and behavioral evolution. The hypothesis holds that antagonistic selection for a large neonatal brain and a narrow, bipedal-adapted birth canal poses a problem for childbirth; the hominin "solution ...Plus de détails
Products – Hardinge
Jones & Shipman 10 ; Universal OD/ID Cylindrical Grinders. By the use of most modern manufacturing means next generation technology is being created, which can meet the customers technical and economical requirements today and tomorrow. Wherever highly accurate grinding is required, Kellenberger precision grinding machines are in use ...Plus de détails
Sanjana Lab | papers
2021-10-30 · Sanjana Lab | papers. Transcriptome-wide Cas13 guide RNA design for model organisms and viral RNA pathogens. Guo X, Rahman JA, Wessels H, Méndez-Mancilla A, Haro D, Chen X, Sanjana NE. Cell Genomics (2021). bioRxiv preprint.Plus de détails
Exploring preferences for place of death with terminally ...
2009-7-15 · Objective To explore the experiences and perceptions of general practitioners and community nurses in discussing preferences for place of death with terminally ill patients. Design Qualitative study using semistructured interviews and thematic analysis. Participants 17 general practitioners and 19 nurses (16 district nurses, three clinical nurse specialists).Plus de détails
Opposing reactions in coenzyme A metabolism sensitize ...
2019-2-1 · Ballinger et al. identified a small molecule that inhibits the enzyme phosphopantetheinyl transferase (PptT), which is crucial for biosynthesis of mycobacterial structural and virulence lipids (see the Perspective by Mizrahi and Warner). Treatment resulted in selective killing of the bacteria in vitro and in a mouse model.Plus de détails
(PDF) Occupational Hazards in Dentistry
Legnani et al 72 made an a ssessment of the a erosol . ... Rowe Nh, Drach Jc, Shipman C Jr, Young Sk. Prevalence Of Herpes Simplex Virus . ... Jones Dl.Rees Td.Plus de détails
Interplay between hevin, SPARC, and MDGAs: Modulators …
2021-7-1 · The hevin FS-EC and SPARC FS-EC (Hohenester et al., 1997) structures feature striking differences despite their high level of sequence identity (56% for the FS domain and 63.3% for the EC domain, respectively) (Figures 2A and 2B).Unexpectedly, the hevin and SPARC EC domains show dramatic structural differences; only 94 C α residues out of 128 (hevin) and 150 (SPARC) residues …Plus de détails
Peer-Reviewed Publications about COVID-19 (Coronavirus) …
Response to Tembhre et al.: ''Enhanced expression of angiotensin-converting enzyme 2 in psoriatic skin and its upregulation in keratinocytes by interferon-γ: implication of inflammatory milieu in skin tropism of SARS-CoV-2''. JR Gehlhausen ; CJ Ko ; W Damsky The British journal of dermatology 2020Plus de détails
Diverse cell junctions with unique molecular composition ...
2019-10-29 · The integrity and organization of animal tissues depend upon specialized protein complexes that mediate adhesion between cells with each other (cadherin-based adherens junctions), and with the extracellular matrix (integrin-based focal adhesions). Reconstructing how and when these cell junctions evolved is central to understanding early tissue evolution in animals.Plus de détails
Jones & Shipman ID/OD Grinder, S/n 45899, Push Button ...
2021-5-17 · Jones & Shipman ID/OD Grinder, S/n 45899, Push Button Controls, (Maint. 91), (Asset 00044), (Plant 2)Loading Fee$100. Auction Details. Well Maintained and Thriving Machine Shop Is Selling Unused Assets! Ends from. Jun 17, 2021 10am ET Date Format.Plus de détails
Cell Adhesion, Polarity, and Epithelia in the Dawn of ...
2004-10-1 · Cano et al. and Pérez-Moreno et al. have identified the E-cadherin transcriptional repressors Snail and the mouse E12/E47 that are members of the zinc finger family and product of the E2A gene, respectively. Both interact with the E-cadherin palindromic element E-pal, present in E-cadherin promoter, and silence its expression.Plus de détails
JONES, machines & equipment d´occasion à vendre ...
Jones & Shipman Model 1310 Cylindrical Grinder, 8 x 18"Capacity, Universal, Internal Spindle, Equipment Coolant Please Note: This lot is located in Essex, UK and will be loadedfree of charge to a …Plus de détails
The Immune Landscape of Cancer
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across cancer types, we identified six immune subtypes-wound healing, IFN-γ dominant, inflammatory, …Plus de détails
and the City (TV Series 1998–2004)
and the City (TV Series 1998–2004) cast and crew credits, including actors, actresses, directors, writers and more.Plus de détails
Wnt antagonist DKK1 acts as a tumor suppressor gene …
The functional significance of Wnt antagonist DKK1 has not been investigated in renal cell carcinoma (RCC). Therefore, we hypothesized that DKK1 may be a tumor suppressor gene and is epigenetically silenced, thus decreased DKK1 may cause progression of RCC. To assess the function of DKK1, we established stable DKK1 transfected cells and monitored them regarding cell viability, colony formation ...Plus de détails
Parenting Knowledge, Attitudes, and Practices
This chapter responds to the first part of the committee''s charge—to identify core parenting knowledge, attitudes, and practices that are associated with positive parent-child interactions and the healthy development of children ages birth to 8. The chapter also describes findings from research regarding how core parenting knowledge, attitudes, and practices may differ by specific ...Plus de détails
(PDF) Current issues in fitness for work certification
Stoeber K, et al. Immunoassay for urothe-lial cancers that detects DNA replication. protein Mcm5 in urine. Lancet 1999; 354: 1524-1525. Cu r r e n t i s s ue s i n fi t n e s s f o r. work ...Plus de détails
Lymphocyte access to lymphoma is impaired by high ...
2021-10-26 · As a hint to their mechanosensitive properties, the integrity of HEVs is strongly compromised during solid stress in metastatic LNs (Jones et al., 2021) and in LNs after surgical or pharmacological deprivation of the afferent lymph flow (Hendriks and Eestermans, 1983; Mebius et al., 1991; Chang et al., 2019).Plus de détails
EEA1, a Tethering Protein of the Early Sorting Endosome ...
2017-10-13 · EEA1 is an early endosomal Rab5 effector protein that has been implicated in the docking of incoming endocytic vesicles before fusion with early endosomes. Because of the presence of complex endosomal pathways in polarized and nonpolarized cells, we have examined the distribution of EEA1 in diverse cell types. Ultrastructural analysis demonstrates that EEA1 is present on a subdomain of the ...Plus de détails
Somatic Mutational Landscape of Splicing Factor Genes …
Seiler et al. report that 119 splicing factor genes carry putative driver mutations over 33 tumor types in TCGA. The most common mutations appear to be mutually exclusive and are associated with lineage-independent altered splicing. Samples with these mutations show deregulation of cell-autonomous pathways and immune infiltration.Plus de détails
Lymphocyte access to lymphoma is impaired by high ...
2021-10-26 · Consistent with a leading function of CCR7 in lymphoma cell homing (Rehm et al., 2011), Eμ-Myc cells were preferentially located within proximity to HEVs, at the border of the paracortex and in the cortical ridge (Figures 2A and S2A–S2C).We observed a gradual decrease of PNAd expression depending on the proximity of vessels to tumor cells (Figure 2B).Plus de détails
The Bold and the Beautiful (TV Series 1987– )
2 · The Bold and the Beautiful (TV Series 1987– ) cast and crew credits, including actors, actresses, directors, writers and more.Plus de détails
Human Origins Studies: A Historical Perspective ...
2010-7-29 · Research into the deep history of the human species is a relatively young science which can be divided into two broad periods. The first spans the century between the publication of Darwin''s Origin and the end of World War II. This period is characterized by the recovery of the first non-modern human fossils and subsequent attempts at reconstructing family trees as visual representations of ...Plus de détails
Comprehensive Characterization of Cancer Driver Genes …
Identifying molecular cancer drivers is critical for precision oncology. Multiple advanced algorithms to identify drivers now exist, but systematic attempts to combine and optimize them on large datasets are few. We report a PanCancer and PanSoftware analysis spanning 9,423 tumor exomes (comprising …Plus de détails
Marriage & Divorce
Marriage records, whether created by a civil authority or a religious clergyman, show a great variety of information. Divorce records often reveal a previous marriage date as well as other relationships. These records are a valuable tool to help you link family members together and …Plus de détails
A test of vision training and potential antecedents to ...
The results, combined with prior findings about the positive influence of distant timespan on vision formation (Shipman et al., 2010; Thoms & Greenberger, 1998) and leaders'' ethical decision ...Plus de détails
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